What is Foot-and-Mouth Disease (FMD) in Animals?

Foot-and-Mouth Disease is a highly contagious viral disease that causes significant economic losses in the livestock sector. So, what is foot-and-mouth disease? This disease primarily affects cloven-hoofed animals and spreads rapidly among both large and small ruminants. Symptoms of foot-and-mouth disease in animals include high fever, loss of appetite, depression, and especially a drop in milk production. Infected animals develop vesicles (blisters) on their mouths, noses, teats, and feet. The rupture of these vesicles leads to extensive ulcerative wounds, prolonging the healing process and reducing the animal's quality of life.

Foot-and-mouth disease can be particularly fatal for young animals and has serious negative effects on the overall health of the animals. Additionally, the disease causes significant losses in milk and meat production. A notable decrease in milk yield is especially observed in cows. These losses pose substantial economic challenges for livestock enterprises, and due to the disease's potential for rapid spread, it can also lead to trade restrictions and severe commercial barriers.

What Are the Symptoms of Foot-and-Mouth Disease in Animals?

Symptoms of foot-and-mouth disease (FMD) vary depending on the animal species, the strain of the virus, and the route of infection. Clinical signs differ between cattle and small ruminants.

In cattle, symptoms include fever, loss of appetite, depression, excessive salivation, and a noticeable drop in milk production. Vesicles (blisters) appear around the mouth, nose, teats, and feet. In small ruminants, symptoms tend to be milder, with lameness being the most prominent sign. Oral lesions are smaller and resolve more quickly compared to those in cattle.

How Is Foot-and-Mouth Disease Diagnosed?

In animals, signs such as excessive salivation around the mouth, frothy discharge, and lesions between the hooves are key indicators for preliminary diagnosis. Lesions may also be present on the udder and teats, though these alone are not sufficient for a definitive diagnosis.

Foot-and-mouth disease should be rapidly identified in animals showing clinical signs, especially in regions where the disease is prevalent. Laboratory tests must be performed on tissue samples to confirm the diagnosis. Quick identification is crucial to control the disease and prevent its spread. FMD is a notifiable disease, and if suspected, a veterinarian should be contacted immediately to begin the diagnostic and treatment process.

What Are the Types of Foot-and-Mouth Disease?

Due to the virus having many types and subtypes, foot-and-mouth disease can present in various forms. The high mutation rate of the virus leads to constant emergence of new variants, making cross-immunity weak and disease control difficult. This diversity in virus types increases the risk of outbreaks and complicates prevention efforts.

In Turkey, several FMD virus types have caused outbreaks over the years. Currently, types O1, A Iran, and ASIA1 are prevalent in the country.

How Is Foot-and-Mouth Disease Transmitted Among Animals?

One of the most frequently asked questions is, “How is foot-and-mouth disease transmitted?”

FMD spreads through body fluids like respiratory secretions, skin, milk, and semen from infected animals. The disease can also be transmitted through contaminated animal products, equipment, vehicles, people, and wild animals. The virus is highly resilient in the environment and can remain infectious on surfaces like wool, hides, and straw for extended periods. Short-range aerosol transmission is also possible.

The virus doesn’t need a live host to spread. Trucks used for transporting animals, milking equipment, barns, and even caretakers’ clothing can play a role in transmission.

The FMD virus dies after 30 minutes at 60–65°C and instantly at 85°C. However, it spreads more easily in moist, cool, and dark environments.

Treatment of Foot-and-Mouth Disease in Animals

While there’s no specific antiviral cure for foot-and-mouth disease (FMD), treatment focuses on relieving symptoms and preventing secondary infections. Innovative approaches like immune-boosting micronutrient cocktails (a mix of vitamins and trace elements tailored per animal) can help enhance resistance. Though antibiotics don’t fight the virus, they’re commonly used to prevent opportunistic bacterial infections.

In cattle, especially dairy cows, pain relievers and anti-inflammatory drugs are prescribed to ease discomfort and aid recovery. A practical and creative treatment addition is the use of natural wound care solutions, such as herbal antiseptic sprays or clay-based pastes on foot and mouth lesions, which both soothe and disinfect. Ensuring strict hygiene, especially on oral and hoof lesions, remains vital to avoid complications.

Innovative Prevention Methods for FMD

The most effective and conventional defense is routine vaccination every 4 to 6 months. But that’s just the beginning. Farmers can strengthen biosecurity with creative measures like:

  • UV sanitation lights at barn entrances to kill surface viruses.

  • Smart tagging systems to track animal movements and isolate suspect cases swiftly.

  • Ozone mist disinfection tunnels for workers and equipment entering high-risk zones.

Even turning barn interiors into “clean zones” with color-coded areas (red for quarantine, green for healthy animals) can help maintain disease-free sections effectively.

What to Do If FMD Is Detected

Once a case is suspected, quick isolation is key. Segregate sick animals, disinfect contaminated areas, and destroy bedding materials. Vets should send samples for lab confirmation immediately. Quarantine measures are enacted, and emergency vaccination protocols for nearby livestock are triggered.

Consider incorporating digital alert systems or farm management apps that notify nearby farmers and authorities in real time, reducing the window for virus spread.

Can Humans Catch Foot-and-Mouth Disease?

The burning question—Can humans get FMD? The answer is yes, but rarely. Direct contact with infected animals or consuming unpasteurized milk/meat can pose a risk. When symptoms occur in humans, they’re generally mild—like a temporary flu with blisters in the mouth or on the hands.

For farmers, workers, and vets, basic hygiene practices—gloves, face shields, changing clothing before and after barn entry—are essential. Taking these steps ensures that the answer to "Does FMD affect humans?" remains: technically yes, but practically negligible.

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